In the one-nave building, there are some works that are fundamental to the history of Italian art, including three polyptychs by Vittore Crivelli (c. 1440-1502) and one by Girolamo di Giovanni da Camerino (1449-1503), presumably dated 1473. The church also houses an ancient organ, on which Giovanni Fedeli worked, while other special features include the altar of the Neapolitan school, at the base of which are majolica tiles, one of the earliest examples of its kind.