Since the late 1500s, the Via Lauretana has served as the main pilgrimage route to the Holy House of Loreto, with its various branches and side paths. It connects with the international network of Faith Itineraries: from the northeast, the Via Romea, from the northwest, the Via Francigena, and from the south, the Via Aprutina. Other routes—such as the Clementina, the Pioraco, the Regina, the Abruzzo, the Macereto and Visso, the Verchiano, and the Jesi routes—also guided pilgrims to Loreto and now form part of the network known as the "Cammini Lauretani". Traveling north from Roma, one encounters the landscapes and significant sites of upper Lazio, Umbria, and the Marche, regions rich in history, scenic beauty, and places of faith.