There are plenty of possible itineraries to enjoy the many splendors of this land. Starting from the main town, highly-recommended is a visit to the Ceramics Museum, Italy's most important, and decorated by items from the best pottery workshops of the Renaissance era. Between the 14th and the 17th Centuries, a majolica industry of exceptional importance flourished in Pesaro, in a style of decoration inspired by Raffaello during the 16th century. 
Pesaro offers many sightseeing opportunities, starting from the town streets around Piazza del Popolo and the Palazzo Ducale to the Museo Civico (Civic Museum, includes the Ceramics Museum), and the Pinacoteca with works by Giovanni Bellini, Vitale da Bologna and Guido Reni. On the opposite side of the Civic Museum is the Oliverian Archeological Museum, with valuable artworks exhibited in the 17th-Century halls of Palazzo Americi. The Rocca and its cylindrical towers, built by Luciano Laurana  for Costanzo Sforza in 1474-87 comprise a prime example of 15th-Century architecture. Pesaro is also  the birthplace of composer Gioacchino Rossini, whose home-museum is open to visitors. Every year, the conservatory and theatre, both named after him, host the Rossini Opera Festival and draws enthusiasts from all over the world. Also meriting vists are two villages built on sea cliffs outside of Pesaro: Fiorenzuola di Focara, a picturesque Medieval village, and Casteldimezzo with its 13th-14th Century walls. Afterwards, a drive to Gradara is recommended, a delightful Medieval village that maintains its original walls made up of towers and battlements, and the square castle, an authentic Medieval environment. Fano is a town with a wealth of historical landmarks, such as the Arch of Augustus and the Palazzo Malatesta, home to the Museo Civico and Pinacoteca (civic museum and art gallery), with collections ranging from the Neolithic period to the present time. 

Moving on to Urbino, be sure to see one of the most evocative sites here: the Fonte Avellana hermitage and the Romanesque-Gothic church, mentioned by Dante in the 21st Canto of the Paradiso. Visitors to Urbino will find its grandeur to be quite captivating. Surrounded by 16th-Century walls built by the Montefeltro family, first is the Palazzo Ducale, with its winged façade that opens itself out to the city. The Palace is a symbol of a new, more humanistic architecture, where the geometric rigor of proportion dominates. The ‘Staircase of Honor’, decorated by Ambrogio Barocci, conducts visitors into the Galleria Nazionale delle Marche, a Palace museum with invaluable artworks. In Duke Federico’s apartment reside two masterpieces by Piero della Francesca, The Flagellation and The Madonna of Senigallia, while in the Duchess’s apartment are Raffaello’s La Muta, The Blessing Christ, attributed to Bramantino, along with Titian's The Last Supper and The Resurrection, to name but a few. Finally, the Cathedral and Museo Diocesano (Diocesan Museum), re-built in the Neoclassical style after the 1789 earthquake. From there, the visitor can walk along Via Raffaello to arrive at Raffaello Sanzio’s birthplace, which still displays engravings and reproductions of his masterpieces. Urbino's extraordinary Renaissance art and architecture, which blend superbly with its medieval past, led to Urbino being listed as a UNESCO World Heritage Site. 
Also visit the Palazzo Ducale, Sant’Angelo in Vado and Mercatello sul Metàuro at Lamoli Abbey, which can be reached by driving through the town centers of Urbania from Urbino.